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特里斯坦·德弗里恩德（Tristan Devriendt）是一名成功的医学院学生，也是个十足的花花公子。他生活中的一切似乎都很完美，并且正在努力争取到一位著名神经外科医生手下的实习名额。直到有一天，他发现自己头上长了个肿瘤。跟随他一起经历这场挣扎，见证他在《肿瘤觉醒》（Sense for Tumor）中的全新人生轨迹。

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Peabody, Massachusetts. A sixth-year high school senior is given the opportunity to graduate by making a movie about why his hometown is such a great place to live. Only one problem... in his eyes, it isn't.

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Meet Saotome Ai, a high school girl from a well-to-do family. When she was a small child, she was in an accident that resulted in a young boy being permanently scarred between his eyes while she emerged unscathed. The young boy saved her life and although she never knew who he was, she never forgot him. Meet Taiga Makoto, a young man with a scar between his eyes who has had a rough life, but has emerged as a rough, tough bully - a thug and a brawler and about as rude as they come - all of which he blames on the incident that gave him his scar. When Ai and Makoto run into each other again, Ai feels guilt for what Makoto has become and decides to intervene and rehabilitate him. But is he a diamond in the rough, or just a bully?

Four friends who are nearly turning 30 need to work together in order to fulfill their dreams.